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pentobarbital will decrease the extent or result of fentanyl intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers may lead into a lessen in fentanyl plasma concentrations, not enough efficacy or, perhaps, advancement of the withdrawal syndrome in the a

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